Pathophysiology of Bronchial Asthma

The three components which make up the composite course of action in pathophysiology of bronchial asthma are: airway inflammation, bronchial hyper-responsiveness and intermittent airflow impediment.

Airway inflammation is caused due to some specific reasons. And these reasons are a good indicator to whether the asthma is sub-acute, acute or chronic. Some of the other indicators that assist the diagnosis are the over secretion of mucus, bronchial reactivity and edema in the air passage: all of which result in obstruction of the sir flow. Further investigation may reveal permeation of eosnophils in varying degrees, damage of epithelium and mucus hyper-secretion.

Active T lymphocytes, mast cells, epithelial cells eosnophils and macrophages etc. can be seen as the reason for airway inflammation in pathophysiology of bronchial asthma. An examination of epithelial cells, fibroblasts and other air passage cells will show the severity of the asthma.

Another symptom in pathophysiology of bronchial asthma is the bronchial hyper activity or hyper-responsiveness to external stimuli. This is measured by causing direct stimulation of the smooth muscle of the airway as well as through indirect stimulation with substances from mast cells or other mediator-secreting cells. The results that are read from the hyper-responsiveness would give the level (severity) of the asthma.

The airflow obstruction is another approach in pathophysiology of bronchial asthma to evaluate the seriousness of asthma. Obstruction in the airway could be due to a series of reasons among which could be the edema of the airway, remodeling of the airway, the formation of a stubborn mucous plug in the airway, acute constriction of the bronchi, etc. The first asthmatic response, as per the pathophysiology of bronchial asthma is the acute bronchi-constriction as a reaction to a mediator release which happens when someone comes into contact with an allergen.

Airway edema follows the process with a minimum and maximum gap of 6 to 24 hours. The mucus plug formation, which is the third component, needs some weeks to grow and disappear. If no other mode of reversing the obstruction formed in the airway is found the airway remodeling has to be done, which is the last component.

Since many other ailments, other than asthma, can also show the same symptoms and cell changes as asthma the pathophysiology of bronchial asthma becomes a controversial and intricate procedure. Hence, the ability to accurately diagnose the indicators and judge requires a lot minute details and can only be gained from experience.

Related articles

Alternative Asthma Cure

Alternative Asthma Medicine

Asthma And Allergy Medication Options

How to Get the Best Asthma Attack Home Remedy

Lemon as Asthma Attack Relief

Asthma Attack Treatment

Bronchial Asthma Diagnosis And Treatment Principle

How to Diagnose and Treat Asthmatic Bronchitis

More Treatment For Asthma Condition

Natural Asthma Remedies And Treatment

Natural Treatment And Solution For Asthma

Natural Cure for Asthma

Facts About New Asthma Drug Treatment

Over-The-Counter Asthma Treatment

Pathophysiology of Bronchial Asthma